The midface, in aesthetic and anatomic terms, is the part of the face from the lower eyelids to the upper lip. At first glance, it may not seem that there is a lot going on here. However, more careful analysis shows that aging in the midface is complicated and multifactorial. In addition, changes here play an extremely important part in the overall aesthetic changes of the aging face. The subtle but complex anatomical and functional issues of the midface have inspired a similarly complex web of surgical, non-surgical, and minimally-invasive treatments. This includes everything from the nearly ubiquitous Botox® Cosmetic and soft-tissue fillers, to less commonly performed operations like the endoscopic midface lift.